After few years of intense development, the team is now able to design and integrate silicon micro-channel cooling devices for thermal management of Silicon-Pixel sensors and their R/O electronics. The achievable cooling efficiency is unparalleled in terms of combined reduction of material budget, reduction of junction temperature difference and uniformity of temperature distribution. The first approved application in an experiment is for the GTK detector of NA62, for which ultra-thin (130 um) silicon devices based on single-phase liquid flow are presently in production (link). In a collaborative effort with LHCb, more complex devices for the upgrade of the VELO detector are also being prototyped at present (link).